Immunoglobulin – IgA, IgM & IgG
The plasma cells of the immune system produce certain types of proteins – immunoglobulins (antibodies) in response to foreign substances. Bacteria, viruses, parasites and other harmful microorganism and antigens are recognised as foreign by the body, and therefore, the body’s immune system produces antibodies against them to offer protection.
Immunoglobulin Types: Immunoglobulin M, Immunoglobulin G (IgG), Immunoglobulin A (IgA), Immunoglobulin D (IgD), and Immunoglobulin E (IgE). An immunoglobulin test is performed to measure immunoglobulins or antibodies level in the blood.
Why the test is ordered?
The test may be ordered to measure the predominant immunoglobulin types (IgA, IgG and IgM) in the blood and to determine their levels. It gives critical information pertaining to the immunological health of an individual and thus helps in determining several health conditions that affect the levels of one or more of these immunoglobulins.
When is the test recommended?
When a physician suspects any abnormality or immunoglobulin deficiency in a patient owing to the symptoms, such as sinusitis, lungs infections, chronic diarrhea or infections of the gastrointestinal tract, he or she may order the immunoglobulin test. The test may also be recommended if a physician suspects abnormal or excess antibodies production owing to chronic infection or inflammation in an individual.
How to prepare for the test?
No special test preparation is required.
How is the sample collected?
A blood sample is collected from a vein in the arm.