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Alpha-1 Antitrypsin (A1AT)

Alpha-1 Antitrypsin (A1AT) is a protein that protects the lungs from any damage by regulating the activity of several enzymes that break down proteins and cause damage to the lung tissue. Some individuals suffer from a  deficiency of this enzyme owing to gene mutations and a family history of the deficiency of this enzyme and are at an increased risk of developing a progressive lung disease (emphysema). Newborns and infants with A1AT deficiency suffer from severe liver disease and jaundice. In adults, the deficiency of A1AT increases the risk of severe liver damage, liver cirrhosis and liver cancer. An Alpha-1 antitrypsin test is used to measure A1AT levels in the blood.

Why is the test ordered?

The test is helpful in the diagnosis of A1AT deficiency in the body that causes chronic obstructive pulmonary disease (COPD) or early onset of emphysema in the absence of any apparent risk factors. The test may also be recommended if the condition of asthma is not being resolved after treatment. The test is primarily recommended for infants and young children to help diagnose the cause of unexplained liver damage and persistent jaundice.

When is the test ordered?

The test may be recommended if an individual younger than 40 years experiences the following symptoms:

  • Shortness of breath
  • Chronic cough
  • Bronchitis
  • Any other signs of emphysema

The test may be recommended for infants who show signs and symptoms of liver damage. The test may also be ordered for individuals who have a family history of A1AT deficiency.

How is the sample collected?

A blood sample is collected from a vein in the arm.

How to prepare for the test?

There is no special preparation required for the test.

Patient Testimonials

“Excellence of Apollo Diagnostics is already a recognized fact across India. Adding more strength to their reputation is their caring nature and supportive attitude. I’ll always prefer to take their services than selecting mediocre quality making any compromise with my health.”

Mr. Shahul Hameed, Chennai

Mrs. Turni, Kolkata

“The way Apollo Diagnostics kept me at ease during the sample collection process, the way they supported me to be at my convenience and confidence is really something I’ll always remember. They were also flawless in maintaining the hygiene. Hats off to them!”

Mr. Laxmi Kantham, Hyderabad

“Awesome is probably the one word to express my views about Apollo Diagnostics. Efficiency, punctuality, compassion, sincerity…I’ll give high marks to them in all of these. Great going, Apollo!”

Shivaraj Kadam, Pune

“Thanks for the seamless service. Based on my experience I can assure that, be it quality or punctuality, Apollo Diagnostics is one name to trust and depend on.”

Mr. Thomas, Mysuru

“Excellent sense of timing! The technician arrived right on time. He was really well-trained, in terms of his skill and manner, as well. Apollo Diagnostics is doing a great job.”

Subbalakshmi, Vizag

“Appreciate the quality of service that I’ve received from Apollo Diagnostics. Their competence, caring nature, sincerity, valuing customer’s time – all these together have shaped them as the most trusted diagnostic service provider in the country.
Keep up the good work!

Mrs. Pravati Dash, Bengaluru

“My mother needed a blood test, but was unable to walk due to pain in her leg. A Phlebotomist from Apollo Diagnostics came home and collected the sample. I was informed, via SMS, that the report could be collected from any of the 3 centres in Dibrugarh, downloaded online or even delivered home for a nominal fee. Although the rates were reasonable, my mother also received a senior citizens discount too! This saved my time, money & energy. My aachhe din really seemed to have arrived! Thank you Apollo Diagnostics and hats off for displaying true professionalism.”

Mr. Alokk Kar Dowerah, Dibrugarh

“Whenever I need to have a blood sample collected from home, I ask for Vasu. He is punctual, courteous and so skilled I hardly feel any pain when he draws the sample. Plus, I truly appreciate how quickly the reports are delivered. Thanks Apollo!”

Mr. Sukumar, Film director, Sriram Nagar, Hyderabad

“Their accurate understanding of customer’s needs is one thing that set them apart and ahead of all others. As a result, it becomes easier for them to deliver the right service, that with their matchless efficiency and care to ensure less pain and easily accomplished sample collection. Apollo Diagnostics is simply doing an amazing job!”

Soundarya Abhirami, Hyderabad

“The overall service standard of Apollo Diagnostics is admirably high. The technician was punctual and well-behaved, and has the genuine skill to collect the test sample without troubling the customer. These are probably some of the major reasons for them to be the best in India.”

Mrs. Lakshmi, Chennai

“The most crucial factor with Apollo Diagnostics is that they always train their Phlebotomists so well that the team consistently remains efficient and punctual and we receive a premium quality diagnostic service. Good job. Keep it up.”

Mr. Amit Kumar Patil, Bengaluru