Dengue Fever Ns1 Antigen, Rapid

Frequently Asked Questions (FAQs)

Dengue virus (DV) is a globally distributed flavivirus with 4 distinct serotypes (DV-1 -2 -3 -4) and is primarily transmitted by the Aedesaegypti mosquito. Interpretation: Positive: - The presence of dengue nonstructural protein 1 (NS1) antigen is consistent with acute-phase infection with dengue virus. - The NS1 antigen is typically detectable within 1 to 2 days following infection and up to 9 days following symptom onset. - NS1 antigen may also be detectable during secondary dengue virus infection but for a shorter duration of time (1-4 days following symptom onset). Negative: - The absence of dengue NS1 antigen is consistent with the lack of acute-phase infection. Note: Serological cross-reactivity across the Flavivirus group (Dengue virus, St. Louis Encephalitis, Japanese Encephalitis, West Nile and Yellow Fever virus) is common. As with all diagnostic tests, all results must be correlated with other clinical findings. If the test result is negative and clinical symptoms persist, additional follow-up testing using other clinical methods is recommended. A negative result at any time does not preclude the possibility of an early infection of Dengue virus.