Fsh,lh & Prolactin, Serum

Sample Type Blood
Pre-test Information Days of menstrual cycle has to be specified. Generally, day 2 to 4 of the menstrual cycle is preferred for collection of sample.
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₹ Price ₹ 1500
FSH-LH-Prolactin is a group of tests which help in evaluating the functioning of reproductive organs in females and sometimes, in males. These tests are used as an adjunct to evaluate menstrual irregularities. This test is also used to assess the patients with suspected hypogonadism, predict the ovulation, help in diagnosing pituitary disorders and even evaluate infertility. Primary hypogonadism generally results in elevated levels of basal LH and FSH. Prolactin is most often used to diagnose Prolactinoma (type of tumor of pituitary gland)

Frequently Asked Questions (FAQs)

REFERENCE GROUP REFERENCE RANGE IN mIU/mL

FEMALES

  • * FOLLICULAR PHASE 2.1 – 11.0
  • MID CYCLE PEAK 19.2 – 103
  • LUTEAL PHASE 1.2 – 12.8
  • PREGNANCY < 1.5
  • POST MENOPAUSAL 10.8 – 58.6

MALES 1.2 – 8.6

Abnormal LH levels are interpreted with increased or decreased levels of other fertility hormones such as FSH estrogens progesterone and testosterone. Increased LH levels are associated primary ovarian hypogonadism and gonadotropin secreting pituitary tumors. Decreased LH levels are associated with Hypothalamic GnRH deficiency Pituitary LH deficiency Ectopic steroid hormone production GnRH analog treatment.

FSH:-

REFERENCE GROUP REFERENCE RANGE IN mIU/mL

FEMALES

  • * FOLLICULAR PHASE 2.5 – 10.2
  • * MID CYCLE PEAK 3.4 – 33.4
  • * LUTEAL PHASE 1.5 – 9.1
  • * PREGNANCY < 0.3
  • * POST MENOPAUSAL 23-116

MALES 1.4- 18.1

Abnormal FSH levels are interpreted with increased or decreased levels of other fertility hormones such as LH estrogens progesterone and testosterone.

Increased FSH levels are associated with menopause and primary ovarian hypofunction in females and primary hypogonadism in males.Decreased FSH levels are associated with primary ovarian hyperfunction in females and primary hypergonadism in males. Normal or decreased FSH levels are associated with polycystic ovary disease in females.

PROLACTIN:-

REFERENCE GROUP REFERENCE RANGE IN ng/mL

ADULT FEMALES

  • * PRE-MENOPAUSAL 3.3 – 26.7
  • * PREGNANCY 9.7 – 208.5
  • * POST MENOPAUSAL 2.7 – 19.6

MALES 2.6 – 13.1

Normal prolactin secretion varies with time which results in serum prolactin levels two to three times higher at night than during the day.

Serum prolactin levels during the menstrual cycle are variable and commonly exhibit slight elevations during the mid-cycle. Prolactin levels in normal individuals tend to rise in response to physiologic stimuli including sleep exercise nipple stimulation sexual intercourse hypoglycemia pregnancy and surgical stress.

Prolactin values that exceed the reference values may be due to macroprolactin (prolactin bound to immunoglobulin). Macroprolactin should be evaluated if signs and symptoms of hyperprolactinemia are absent or pituitary imaging studies are not informative.

Increased levels of prolactin upto 100ng/mL are documented with the use of following drugs:

Neuroleptics antidepressants antipsychotics medications for nausea such as metoclopramide birth control pills estrogen analogs dopamine antagonists some blood pressure medications like methyldopa reserpine and opiates.